Kihealth Labs scientist reviewing Intercept IQ precision-diagnostics dashboards beside plasma sample tubes in a bright laboratory

The Intelligence Behind Precision Diagnostics

The Intercept IQ™ Platform is Kihealth Labs' proprietary precision diagnostics platform that integrates advanced molecular technologies, multi-omic data, artificial intelligence, and clinical intelligence into a unified framework for developing next-generation diagnostic assays.

Rather than relying on a single biomarker or technology, Intercept IQ combines multiple layers of biological and clinical information to identify disease earlier, improve diagnostic accuracy, and generate clinically actionable insights across numerous disease areas.

Intercept IQ™ Platform

  1. EDTA blood collection tube held in a gloved hand in a bright laboratory
    1
    Sample Collection
  2. Luminous DNA double helix strand
    2
    Multi-Omic Analysis
  3. Sequencing flow cell and CpG methylation heatmap on a laboratory instrument
    3
    Advanced Molecular Analytics
  4. Neural network of glowing nodes above a silicon processor chip
    4
    Ki Intelligence™ AI Engine
  5. Clinician reviewing a patient risk dashboard on a tablet
    5
    Actionable Clinical Intelligence
  6. Pancreatic islet cells protected by a shield of light
    6
    Disease Interception
Platform Architecture

A Multi-Layer Precision Diagnostics Platform

Every disease is biologically complex. No single technology captures the full picture.

Intercept IQ was designed to integrate complementary molecular technologies into one scalable platform capable of developing highly sensitive diagnostic assays across multiple therapeutic areas.

Molecular Signal
Biological & Clinical Context
Intelligence
Layer 1Molecular Signal
04

Detection chemistry that resolves biology from a single blood draw.

Layer 2Biological & Clinical Context
03

Layers that give the molecular signal meaning for a specific patient.

Layer 3Intelligence
01

The computational layer that turns integrated data into a clinical answer.

Component 01 / 08Molecular Signal

Cell-Free DNA

Measures circulating DNA released from damaged or dying cells, enabling non-invasive assessment of tissue-specific injury before structural changes become clinically apparent.

Select a layer component to inspect

Platform Workflow

How the Intercept IQ™ Platform Works

Every patient or research sample processed through the Intercept IQ™ Platform follows a standardized analytical workflow that transforms complex molecular and clinical information into clinically actionable intelligence. By integrating advanced laboratory science, patient-specific context, and the proprietary Ki Intelligence™ engine, the platform delivers insights designed to support earlier detection, predictive modeling, longitudinal monitoring, and more informed clinical decision-making.

Precision diagnostics laboratory analyzing molecular samples on the Intercept IQ™ platform
Step01

Sample Collection

Patient or research samples are collected using validated collection methods that preserve molecular integrity for high-quality laboratory analysis.

Specimen types
Whole BloodPlasmaSerumAdditional validated specimen types
Step02

Molecular Analysis

Disease-specific Intercept assays analyze highly sensitive molecular signals using advanced laboratory technologies. Depending on the application, the platform evaluates multiple biological dimensions to generate precise molecular data.

Technologies
Cell-Free DNA (cfDNA)DNA MethylationDroplet Digital PCR (ddPCR)Protein BiomarkersMulti-OmicsNext-Generation Sequencing
Step03

Clinical Context Integration

Molecular findings are integrated with patient-specific clinical information to provide a more comprehensive understanding of disease risk and biological activity.

Integrated inputs
Family HistoryMedical HistoryLaboratory ResultsMedicationsDemographicsLifestyle FactorsPrevious Intercept IQ Results
CORE ENGINE

Ki Intelligence™ Engine

The proprietary Ki Intelligence™ engine integrates molecular biomarkers, clinical information, longitudinal patient data, and continuously expanding research datasets to identify complex biological patterns that may not be apparent through traditional diagnostic approaches.

Advanced predictive models evaluate disease probability, biological activity, longitudinal change, and individualized risk to generate clinically meaningful insights.

Inputs
Molecular Biomarkers
Clinical Context
Longitudinal Data
Research Datasets
KI INTELLIGENCE™
Model outputs
Disease Probability
Risk Stratification
Longitudinal Change
Pattern Recognition
Predictive ModelingPopulation IntelligenceContinuous Learning
Step05

Actionable Clinical Intelligence

The platform transforms complex molecular and clinical information into intuitive reports that support earlier detection, patient monitoring, and evidence-informed clinical decision-making.

Report modules
Disease Risk AssessmentBiomarker SummaryLongitudinal TrendsClinical InterpretationRecommended Follow-UpPatient Monitoring
Step06

Longitudinal Precision Monitoring

Each additional Intercept IQ assessment contributes to a longitudinal molecular profile, enabling physicians and researchers to monitor biological change over time rather than relying on isolated diagnostic snapshots.

Tracking serial measurements helps identify disease progression, evaluate therapeutic response, refine individualized risk assessments, and support more personalized care strategies.

SERIAL MOLECULAR SIGNAL
ELEVATEDMONITORINGREFERENCE RANGE050100INTERVENTION88Baseline813 mo626 mo4412 mo3118 mo2424 moSERIAL ASSESSMENTS OVER TIME
The Outcome

From Molecular Data to Clinical Intelligence

The Intercept IQ™ Platform integrates advanced molecular diagnostics, clinical context, and the proprietary Ki Intelligence™ engine into a unified precision diagnostics ecosystem. Rather than reporting individual biomarkers in isolation, the platform transforms diverse biological signals into actionable intelligence.

Earlier Detection

Molecular signals surface biological change before conventional markers move.

Predictive Modeling

Ki Intelligence™ translates complex patterns into individualized risk.

Longitudinal Monitoring

Serial assessments track trajectory, not isolated snapshots.

Precision Medicine

One validated platform extended across multiple disease areas.

Physician and research scientist reviewing Intercept IQ molecular diagnostic results on a large display in a sunlit clinical laboratory

A Scalable Precision Diagnostics Ecosystem

The Intercept IQ™ Platform serves as the scientific and computational foundation for every diagnostic program developed by Kihealth Labs. Rather than creating independent technologies for each disease, Intercept IQ enables the development of disease-specific assays using a common platform that integrates advanced molecular diagnostics, proprietary biomarkers, multi-omic data, and the Ki Intelligence™ engine.

Each diagnostic application is optimized for a specific clinical indication while leveraging the same proven platform for molecular analysis, predictive modeling, and longitudinal patient monitoring.

Available

Beta Intercept™

Diabetes & Metabolic Disease

Early detection of pancreatic beta-cell injury and metabolic dysfunction.

Beta Intercept™ is the flagship diagnostic application built on the Intercept IQ™ Platform. By integrating cell-free DNA, tissue-specific DNA methylation, advanced biomarkers, metabolic data, and the Ki Intelligence™ engine, Beta Intercept™ is designed to identify beta-cell injury at the earliest stages of disease — supporting earlier intervention, longitudinal monitoring, and precision metabolic care.

Key applications
Type 1 DiabetesType 2 DiabetesPrediabetesMetabolic SyndromeGLP-1 Therapy MonitoringBeta-Cell Health Assessment
Learn more
In Development

Neuro Intercept™

Neurology

Biomarker-based assessment of neurodegenerative disease processes.

Neuro Intercept™ applies the Intercept IQ™ Platform to neurological disease by integrating molecular biomarkers, clinical information, and predictive analytics to detect biological changes associated with neurodegeneration before significant clinical decline.

Key applications
Alzheimer's DiseaseMild Cognitive ImpairmentParkinson's DiseaseMultiple SclerosisOther Neurodegenerative Disorders
Learn more
In Development

Onco Intercept™

Oncology

Molecular detection strategies for early cancer identification and monitoring.

Onco Intercept™ leverages the Intercept IQ™ Platform to identify disease-specific molecular signatures associated with cancer development, progression, and therapeutic response, supporting the future of precision oncology.

Key applications
Pancreatic CancerTreatment MonitoringDisease ProgressionRecurrence Surveillance
Learn more
Future Platform Expansion

Future Disease Programs

Additional indications in early exploration, each inheriting the same molecular, computational, and quality infrastructure.

Transplant Monitoring
Future Program
Precision Longevity
Future Program
Intelligence Architecture

Why an Integrated Platform Matters

Disease is rarely driven by a single biological signal. Traditional diagnostics often evaluate one biomarker in isolation, providing only a limited snapshot of a patient's health.

The Intercept IQ™ Platform integrates multiple layers of molecular, clinical, and computational intelligence to create a more comprehensive understanding of disease biology. By evaluating complementary biological dimensions together, the platform is designed to deliver earlier, more confident, and more clinically meaningful insights.

The Three Layers of Clinical Intelligence
Layer 01

Biological Signals

The raw biological information generated from every patient sample.

01Cell-Free DNA02DNA Methylation03Biomarkers04Proteomics05Multi-Omics06Next-Generation Sequencing07Clinical Chemistry08Longitudinal Samples
Layer 02

Computational Intelligence

Raw molecular information is transformed into meaningful biological intelligence.

Ki Intelligence™Active inference
01Pattern Recognition02Predictive Modeling03Risk Stratification04Population Intelligence05Longitudinal Learning06Clinical Correlation07Continuous Optimization
Network-node brain model rendered above a processor chip beside a DNA helix and analytical charts, representing computational molecular intelligence
Layer 03

Clinical Insights

Complex biology becomes actionable clinical intelligence.

Disease Risk Assessment
Calibrated probability
01
Biomarker Interpretation
Signal in context
02
Longitudinal Trends
Change over time
03
Therapeutic Response
On / off treatment
04
Personalized Monitoring
Patient-specific cadence
05
Clinical Recommendations
Actionable next step
06
A Clear Contrast

Single Biomarker vs. Integrated Intelligence

The difference between a single data point and a comprehensive molecular picture is the difference between a snapshot and a living portrait of disease biology.

Traditional Diagnostics

Single Biomarker

AssayLab Report
  • Limited biological context
  • Static point-in-time measurement
  • Reactive disease assessment
  • Separate testing for each condition
  • Limited longitudinal intelligence
Intercept IQ™ Platform

Integrated Precision Intelligence

cfDNAMethylationProteomicsClinical
Ki Intelligence™
Intelligent Clinical Report
  • Multi-dimensional biological analysis
  • Molecular plus clinical integration
  • Predictive modeling
  • Longitudinal monitoring
  • Personalized risk assessment
  • Scalable across multiple disease programs
Platform Advantages

What Integrated Intelligence Means for Clinical Care

Six measurable advantages that an integrated molecular intelligence platform delivers over traditional, single-biomarker testing.

01

Earlier Detection

Identify biological changes before traditional clinical markers become abnormal.

02

Greater Diagnostic Confidence

Integrate multiple biological dimensions to support more informed clinical interpretation.

03

Reduced Biological Uncertainty

Evaluate complementary molecular signals rather than relying on a single biomarker.

04

Longitudinal Monitoring

Track biological change over time to better understand disease progression and therapeutic response.

05

Personalized Clinical Intelligence

Combine molecular data with patient-specific clinical information for individualized risk assessment.

06

Scalable Platform

Expand into new disease indications using the same validated scientific and computational foundation.

Better Data. Better Intelligence. Better Decisions.

The Intercept IQ™ Platform transforms complex molecular and clinical information into actionable intelligence that empowers physicians, researchers, and healthcare organizations to detect disease earlier, monitor patients more effectively, and advance the future of precision medicine.

Platform Outlook

A Platform Built for the Future of Precision Medicine

The future of diagnostics will depend on the ability to integrate diverse molecular and clinical data into cohesive, clinically actionable intelligence.

Intercept IQ™ was built with that future in mind — a continuously evolving precision-diagnostics platform designed to transform scientific discovery into scalable diagnostic solutions.

As new biomarkers are identified, clinical datasets expand, and analytical models mature, the platform becomes increasingly capable — supporting the development of more sophisticated assays across a broad spectrum of diseases.

01

Scientific Discovery

  • New biomarkers
  • Emerging molecular signatures
  • Translational research
  • Disease-specific biological insights
02

Expanding Evidence

  • Clinical datasets
  • Longitudinal patient data
  • Multi-omic information
  • Real-world evidence
03

Evolving Intelligence

  • Ki Intelligence™
  • Predictive analytics
  • Pattern recognition
  • Model refinement
04

Scalable Diagnostics

  • New diagnostic assays
  • Additional disease indications
  • Longitudinal monitoring
  • Precision clinical applications

Every Discovery Strengthens the Platform

Each validated biomarker, clinical dataset, and diagnostic program expands the scientific foundation of Intercept IQ™ — creating a platform that becomes more capable as its evidence base grows.

From Scientific Discovery to Scalable Diagnostic Impact

Intercept IQ™ provides a common scientific and analytical foundation for developing diagnostic solutions across diseases, patient populations, and stages of care.